You may want to consider an organizational approach like the one Mayarra describes in this thread: 1.000.000-loci Memory Palace.
Her management of multiple—and extensive—memory palaces seems like one powerful way to handle a massive amount of information within imagined spaces. If you want something more real-world based, I’d encourage you to read Lynne Kelly’s posts here that describe both a memory journey/walk through her neighborhood, where she has encoded a huge amount of information, and her use of physical memory aids such as the lukasa.
Bob