2704 is right about the kinds of benefits you could see and how those can guide you to a better state of mind. But I did mean you can figure out ways to apply it more directly.
The TL;DR of a project I have is to basically convert affirmations / perspectives / little reframes (ex: Instead of having to do zyx, you get to do xyz.) into little journeys so I can go through them much more meaningfully than just reading a list.
Some clever individual out there thought to teach people with major depression to place happy memories within a memory palace. A week later they could bring back most of those memories, while the control group lost access to several of the ones they brought up. This is… A much bigger deal than it might seem.
There are other experiments and some posts on this forum focused around it, like:
If you spend time doing one of many exercises where you deeply explore your motivations, either for something specific like wanting to pick up a new skill, or more generically “The things I love most are travel, music, and basket weaving” you can put the results into a memory palace. With a little maintenance, that will always be there for you to reference when you need it. Maybe to help you get through the pits in learning a new skill, or to check your deepest loves and motivations against major life choices.
Much of what we do is influenced by the physical environment, and what we keep our minds “pointed” at. If you can use memory techniques to help direct your thoughts and focus, well.