Is this of any help?
If you want a single palace with something like a 1.000 loci, you can add another dimension of difference to them. I got a memory palace that has 10 of the same rooms. Each room got something to it that makes it unique. One room is completely on fire, one room has all furniture made out of trees growing in a certain way, one room is made of ice, you name it. The rooms are the same, but there is something that helps me keep them apart.